Biosynthesis of fungal indole alkaloids
نویسندگان
چکیده
منابع مشابه
Biosynthesis of the indole and Colchicum alkaloids.
There has been enormous progress over the past fifteen years or so in our understanding of the ways in which complex natural products are synthesized in living systems. In the field of alkaloids, as elsewhere, research during the initial phase1 pin-pointed those substances which are used as the common building blocks, examples being acetic acid, ornithine and lysine for the reduced systems, and...
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The hydroxylation of the indole-type alkaloids, yohimbine, alpha-yohimbine, beta-yohimbine, and corynanthine, was achieved with several genera of higher fungi and species of Streptomyces. Microorganisms were found which monohydroxylated these compounds in three different positions. The site of hydroxylation was strain-specific for two strains of Cunninghamella echinulata and C. bainieri.
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Peroxy-containing metabolitesare an interesting group amongbiological active natural compounds. These metabolites contain a peroxide group (-O-O-) in which each oxygen atom is bonded to the other oxygen an to another atom. β-Oxygen in hydroperoxide group is considered as moreactive.Present review describes research on more than 100 natural hydroperoxidesand rare acyclic peroxides isolated from ...
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ژورنال
عنوان ژورنال: Nat. Prod. Rep.
سال: 2014
ISSN: 0265-0568,1460-4752
DOI: 10.1039/c4np00073k